منابع مشابه
Adiponectin and vulnerable atherosclerotic plaques.
High-risk plaques that are vulnerable to rupture demonstrate distinct morphological characteristics. They are differentiated from the lesions responsible for stable coronary artery disease by their large necrotic cores, thin-inflamed fibrous caps, and positive remodeling. Adiponectin is an adipocytokine that is reduced in obesity and type 2 diabetes. Hypoadiponectinemia has been associated with...
متن کاملNuclear Molecular Imaging for Vulnerable Atherosclerotic Plaques
Atherosclerosis is an inflammatory disease as well as a lipid disorder. Atherosclerotic plaque formed in vessel walls may cause ischemia, and the rupture of vulnerable plaque may result in fatal events, like myocardial infarction or stroke. Because morphological imaging has limitations in diagnosing vulnerable plaque, molecular imaging has been developed, in particular, the use of nuclear imagi...
متن کاملMolecular Imaging of Vulnerable Atherosclerotic Plaques in Animal Models
Atherosclerosis is characterized by intimal plaques of the arterial vessels that develop slowly and, in some cases, may undergo spontaneous rupture with subsequent heart attack or stroke. Currently, noninvasive diagnostic tools are inadequate to screen atherosclerotic lesions at high risk of acute complications. Therefore, the attention of the scientific community has been focused on the use of...
متن کاملStabilisation of atherosclerotic plaques
Seppo Ylä-Herttuala1; Jacob Fog Bentzon2; Mat Daemen3; Erling Falk2; Hector M. Garcia-Garcia4; Joerg Herrmann5; Imo Hoefer6; J. Wouter Jukema7; Rob Krams8; Brenda R. Kwak9; Nikolaus Marx10; Marek Naruszewicz11; Andrew Newby12; Gerard Pasterkamp6; Patrick W. J. C. Serruys4; Johannes Waltenberger13; Christian Weber14; Lale Tokgözoglu15 1Chairman of the position paper task force, A.I.Virtanen Inst...
متن کاملVulnerable Atherosclerotic Plaque
Plaque Progression: Often Abrupt, Rarely Predictable Some facts are now certain. First, plaque progression and clinical outcome are not always closely related, and each is poorly predicted by clinical and angiographic variables.1–4 Second, many plaques progress episodically because of episodes of thrombosis triggered by rupture, erosion (denudation), or occasionally endothelial activation or in...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2004
ISSN: 1079-5642,1524-4636
DOI: 10.1161/01.atv.0000142373.72662.20